中科院昆明动物研�I�所导师介绍:徐林_跨考网

　　�U�学家们普遍认�ؓ�H�触可塑性是研究学习记忆的最佳细�?y��u)分子模型�?0多年来的研究�q�展已充分证明突触可塑性参与了记忆的获取、�m固和提取。学习记忆涉及到大脑的许多区域和许多�l�胞(y��u)分子�q�程�Q�而突触可塑性是其中一部分�Q��ƈ不等于学习记忆。通俗地认为是学习记忆�q�程留下的痕�q�V��至今，�H�触可塑性是如何参与学习记忆仍然是个谜。许多工作需要系�l�地研究�Q�如�Q�突触可塑性是否可以传递？�H�触可塑性是如何参与应激、毒品成瘄���异常记忆�Q�神�l�信息编码与�H�触可塑性的关系�Q�这些内容也是本实验室研�I�的��N���Q�如�Q�国家杰出青�q�基金（�H�触可塑性在应激��D��的大脑衰老中的作用）、科学院重要方向�Q�心理依赖性与�H�触可塑性）�?/p>

　　�q�年来发表的�U�研论文�Q?/p>

　　1. Wenyong Xiong a�Q?c�Q?Yuexiong Yang a�Q?Jun Cao a�Q?Huiming Wei b�Q?Chongli Liang b�Q?Shangchuan Yang a�Q?Lin Xu a* �Q?003�Q?The stress experience dependent long-term depression disassociated with stress effect on spatial memory task. Neuroscience Research 46�Q?�Q�： 415-421 [IF=1.77]

　　2. Yuexiong Yang 1�Q?Jun Cao 1�Q?Wenyong Xiong 1�Q?Jichuan Zhang 1�Q?Qixin Zhou 1�Q?Huiming Wei 2�Q?Chongli Liang 2�Q?Jianhua Deng 3�Q?Tianfei Li 3�Q?Shangchuan Yang 1�Q?and Lin Xu1 * �Q?003�Q?Both Stress Experience and Age Determined the Impairment or Enhancement Effect of Stress on Spatial Memory Retrieval. Journal of Endocriology 178�Q?�Q�： 45-54 [IF=2.832]

　　3. Ya Yang1 *�Q?Xigeng Zheng 2*�Q?Yongfu Wang 3�Q?Jun Cao 1�Q?Zhifang Dong 1�Q?Jingxia Cai 3�Q?Nan Sui 2�Q?Lin Xu 1 �Q?003�Q?The Synergistic Action of Stress and Morphine Induced large Long-term Depression in the CA1 Area of the Hippocampus of Anesthetized Rats and Long-term Effect on Drug Seeking Behavior. Journal of Neuroscience �Q�revised�Q?[IF=8.99]

　　4. Yuexiong Yang a�Q?Yueming Mab *�Q?Linxian Ni b�Q?Shengquan Zhao b�Q?Lijun Li b�Q?Jianyin Zhang b�Q?Mao Fan b�Q?Huiming Wei c�Q?Chongli Liang c�Q?Jun Cao a�Q?Lin Xua * �Q?003�Q?Lead Exposure Through Gestation-only Caused Lower Sex Ratio of Male at Birth and Long-term Memory Deficits in Young Adult Offspring. Experimental Neurology �Q�in press�Q?[IF=3.5]

　　5. Huiming Wei�Q?Wenyong Xiong�Q?Shangchuan Yang�Q?Qixin Zhou�Q?Chongli Liang�Q?BangXiong Zeng�Q?Lin Xu �Q?002�Q?Propofol facilitates the development of long-term depression �Q�LTD�Q?and impairs the maintenance of long-term potentiation �Q�LTP�Q?in the CA1 region of the hippocampus of anesthetized rats. Neuroscience Letters�Q?324�Q?�Q�： 181-184. [IF=2.02]

　　6. Lin Xu�Q?Anwyl R�Q?Rowan MJ �Q?998�Q?Spatial exploration induces a reversal of long-term potentiation in rat hippocampus. Nature�Q?394�Q?891-894. [IF=27.338]

　　7. Rowan MJ�Q?Anwyl R�Q?Lin Xu �Q?998�Q?Stress and long-term synaptic depression. Molecular Psychiatry�Q?2�Q?472-476. [IF=6.250]

　　8. Lin Xu�Q?Holscher C�Q?Anwyl R�Q?Rowan MJ �Q?998�Q?Glucorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress. Proc. Natl. Acad. Sci. USA�Q?95�Q?3204-3208. [IF=9.88]

　　9. Lin Xu�Q?Anwyl R�Q?Rowan MJ �Q?997�Q?Behavioural stress facilitate the induction of long-term depression in the hippocampus. Nature�Q?387�Q?497-500. [IF=27.338]

　　10. Lin Xu�Q?Anwyl R�Q?Rowan MJ �Q?997�Q?Role of 5-HT1a receptors and relationship to anxilytic effect. European Journal of Pharmacology�Q?323�Q?59-68. [IF=2.16]

　　联系信息�Q?/p>

　　Email�Q�lxu@vip.163.com

　　地址�Q�昆明市教场东�\32�?a target="_blank">中国�U�学�?/a>昆明动物研究所

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?中科院昆明动物研�I�所